Man in a bathrobe looking at his reflection in a steamy bathroom mirror

All PLHIV pictured and quoted in this website have been prescribed every-2-month VOCABRIA + REKAMBYS. They have given consent for the use of their images and words, and have received remuneration from ViiV Healthcare.

Indication: VOCABRIA injection is indicated, in combination with REKAMBYS injection, for the treatment of HIV-1 infection in adults who are virologically suppressed (HIV-1 RNA <50 copies/mL) on a stable antiretroviral regimen without present or past evidence of viral resistance to, and no prior virological failure with, agents of the NNRTI and INI class.[1,2]


The first head-to-head switch study comparing every-2-month VOCABRIA + REKAMBYS to daily oral therapy[3]

SOLAR investigated the efficacy, safety and treatment experience of participants who were switched to every-2-month VOCABRIA + REKAMBYS (n=454) vs those who continued daily oral therapy with BIC/FTC/TAF (n=227).[3]

The solar study endpoint was met (mITT- E population): Every-2-month VOCABRIA +REKAMBYS was non-inferior to daily oral therapy with BIC/FTC/TAF at month 12 (1.1% with plasma HIV-1 RNA ≥50 copies /ml [n=5/447] vs 0.4 [n=1/223], respectively)[3]



Icon with a person representing a patient

Addressing challenges

Can remove the need for regular daily oral therapy[1,2]

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Patient preference

Preferred by 90% of participants over daily oral therapy with BIC/TFC/TAF[3]

Icon with a tick to represent proven efficacy

Proven efficacy

Non-inferior vs daily oral therapy with BIC/FTC/TAF at 12 months in the SOLAR trial[3]

Sustained efficacy of 2-monthly dosing vs monthly over 152 weeks in the ATLAS- 2M trial[4]

*Participants were suppressed for ≥6 months, virologic suppression defined as HIV-1 RNA <50 copies/mL.[3]

BIC/FTC/TAF=bictegravir/emtricitabine/tenofovir alafenamide; HIV=human immunodeficiency virus; HIV-1=human immunodeficiency virus type 1; INI=integrase inhibitor; NNRTI=non-nucleoside reverse transcriptase inhibitor; PLHIV=people living with HIV-1; RNA=ribonucleic acid.


  1. VOCABRIA Summary of Product Characteristics. ViiV Healthcare.
  2. REKAMBYS Summary of Product Characteristics. Janssen.
  3. Ramgopal MN, Castagna A, Cazanave C, et al. SOLAR 12-Month Results – Randomized Switch Trial of CAB + RPV LA vs. Oral BIC/FTC/TAF. Presented at Conference on Retroviruses and Opportunistic Infections (CROI): February 19–22, 2023. REF-182990.
  4. Overton ET, Richmond G, Rizzardini G, et al. Long-acting cabotegravir and rilpivirine dosed every 2 months in adults with human immunodeficiency virus 1 type 1 (HIV-1) infection: 152-week results from ATLAS-2M, a randomized, open-label, phase 3b, noninferiority study. Clin Infect Dis. 2023;ciad020. doi: 10.1093/cid/ciad020. Online ahead of print.

REKAMBYS (rilpivirine long-acting injection), including the trademark, is owned by the Janssen Pharmaceutical Companies and used under licence by the ViiV Healthcare group of companies. All other trademarks are owned by the ViiV Healthcare group.

PM-GB-CBR-WCNT-230001 - August 2023

Adverse event reporting

Adverse events should be reported. Reporting forms and information can be found at or search for MHRA Yellowcard in the Google Play or Apple App store. Adverse events should also be reported to GlaxoSmithKline on 0800 221441.

If you are from outside the UK, you can report adverse events to GSK/ViiV by selecting your region and market, here.