POSITIVE PERSPECTIVES CROSS SECTIONAL GLOBAL SURVEY
Background
The Positive Perspectives 2 global survey was run by ViiV Healthcare in collaboration with an international, multi-disciplinary Advisory Committee of experts, including HIV clinicians, people living with HIV and patient group representatives. This explored how care and treatment affect the health and wellbeing of PLHIV beyond viral suppression and provided in-depth insights into the challenges that impact the QoL of PLHIV.
The study is helping us to understand and address the unmet treatment needs and challenges faced by PLHIV. The Innovation and Implementation Science team primarily supported with the questionnaire design and the analysis and dissemination of data, particularly relating to a subgroup analysis relating to those ageing with HIV.
Design
Cross-sectional international survey of individuals with HIV-1+ diagnosis, taking ARV drug therapy, and between 18 and 84 years of age. The pooled sample size from 24 countries was 2,112 individuals. Snowball sampling with recruiting from HIV clinics, HIV online groups and social media were used to recruit individuals to participate in this survey.
Conclusions
- Of older adults living with HIV, 23% reported suboptimal health and 26% reported optimal health on all domains. Approximately half the population reported results within these two extremes.
- Geographic disparities exist in self-reported health status. These differences highlight the need for tailoring treatment to narrow inequalities.
- Groups with worst perceived health included those reporting ≥2 comorbidities, suboptimal adherence, and those dissatisfied with treatment.
- Holistic approach to care requires seeking improvements in all aspects of health and considering patients as a whole. Quality communication is needed to alleviate mental distress, which may not be readily discernable to HCPs.
ViiV lead:
Chinyere Okoli
Patricia De Los Rios
Setting
Online
Locations
United States, United Kingdom, Australia, Canada, France, Germany, Italy, Spain, Japan, Mexico, Portugal, Brazil, Russia, Taiwan, Netherlands, Argentina, Austria, Chile, China, Ireland, Belgium, Poland, South Korea, Switzerland, and South Africa
Duration
Oct 2019 – Mar 2021
Category
Health Related Quality of Life
Key study materials
MANUSCRIPT
Preventing Chronic Disease: Public Health Research, Practice, and Policy
Relationship Between Polypharmacy and Quality of Life Among People in 24 Countries Living With HIV
Download
ORAL PRESENTATION
HIV Drug Therapy Conference 2020
Psychological, and Treatment-Related Challenges of a New HIV Diagnosis in Old Age
Download
ORAL PRESENTATION
HIV Drug Therapy Conference 2020
Beyond viral load: Exploring mediating factors for the gap in optimal self-rated health by adherence status among older adults living with HIV.
Download
POSTER
23rd International AIDS Conference
Understanding the changing treatment concerns of older people living with HIV and difficulties with patient-provider communication
Download
ORAL PRESENTATION
23rd International AIDS Conference
CLINICAL AND SOCIODEMOGRAPHIC
CHARACTERISTICS ASSOCIATED WITH
POOR SELF-RATED HEALTH ACROSS MULTIPLE DOMAINS AMONG OLDER ADULTS LIVING WITH HIV
Download
RELATED STUDIES
AUSTRALIA
In collaboration with La Trobe University in Melbourne, Australia, and other partners, we continue to support the development, evaluation and dissemination of a short, validated HIV specific quality of life measure (PozQoL) to help researchers, clinical practitioners and program evaluators to assess the needs of PLHIV
USA
This randomized controlled trial demonstrated how a series of brief online mindfulness audio lessons improves mental health outcomes among older PLHIV (aged 50+) who report some degree of loneliness.
BRAZIL
This study demonstrated how the effective implementation of a clinical care monitoring system increased the number of patients engaged across the care continuum and improved patient outcomes.
Study focus areas
Our implementation research projects have a global reach and focus on improving the HIV prevention and care continuum.
NP-GBL-HVX-WCNT-220049 October 2023
Adverse events should be reported. Reporting forms and information can be found at yellowcard.mhra.gov.uk or search for MHRA Yellowcard in the Google Play or Apple App store. Adverse events should also be reported to GlaxoSmithKline on 0800 221441.
If you are from outside the UK, you can report adverse events to GSK/ViiV by selecting your region and market, here.
